Hydrix Medical introduces

PHYRARI FFR-Wire

Innovative FFR technology for cardiac intervention procedures

Emerging new technology to help increase procedure safety and improve deployment of life-saving stents

In a typical angiogram procedure, a technology called Fractional Flow Reserve (FFR) is often used to measure blood pressure differences either side of a coronary artery stenosis to determine the amount of blood flow to the heart muscle. This information helps to determine if interventional treatment such as a stent is required.

The Phyzhon PHYRARI FFR-Wire is a ground-breaking technology enabling cardiologists to combine diagnosis procedures with delivery of therapy including stents.

Approximately 125,000 coronary angiograms are
performed each year in Australia

Leading to 60,000 Percutaneous Coronary
Intervention (PCI) procedures

During which 12,000 FFR measurements are taken to
determine whether to stent the artery or not

Clinical trials

Hydrix will be facilitating FIH trials of the Phyzhon PHYRARI-FFR in CY22

Contact us if you want to be kept informed of the latest trial updates

For Healthcare Professionals
Relevant FFR related studies

  1. G. Bech, B. Bruyne, N. Pijls, et al. Fractional flow reserve to determine the appropriateness of angioplasty in moderate coronary stenosis: a randomized trial. Circulation. 2001;103(24):2928-2934.
  2. J. Sels, P. Tonino, U. Siebert, et al. Fractional flow reserve in unstable angina and non-ST-segment elevation myocardial infarction experience from the FAME (Fractional flow reserve versus Angiography for Multivessel Evaluation) study. JACC Cardiovasc Interv. 2011;4(11):1183-1189. 
  3. B. Bruyne, W. Fearon, N. Pijls, et al. Fractional flow reserve-guided PCI for stable coronary artery disease. N EnglJ Med. 2014;371(13):1208-1217. 
  4. T. Engstrøm, H. Kelbæk, S. Helqvist, et al. Complete revascularisation versus treatment of the culprit lesion only in patients with ST-segment elevation myocardial infarction and multivessel disease (DANAMI-3—PRIMULTI): an open-label, randomised controlled trial. Lancet (London, England). 2015;386(9994):665-671.
  5. J. Layland, K Oldroyd, N. Curzen, et al. Fractional flow reserve vs. angiography in guiding management to optimize outcomes in non-ST-segment elevation myocardial infarction: the British Heart Foundation FAMOUS-NSTEMI randomized trial. EurHeart J. 2015;36(2):100-111. 
  6. J. Ligthart, K. Masdjedi, K. Witberg, et al. Validation of Resting Diastolic Pressure Ratio Calculated by a Novel Algorithm and Its Correlation With Distal Coronary Artery Pressure to Aortic Pressure, Instantaneous Wave–Free Ratio, and Fractional Flow Reserve. Circulation: Cardiovascular Interventions 2018;11:e006911.
  7. M. Kern and A. Setol. dPR, Another Diastolic Resting Pressure Ratio. Circulation: Cardiovascular Interventions 2018;11:e007540.